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    • Gallery
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      • KENACIN TAB
      • BEETHER INJECTION
      • CHYMOK TAB
      • KINBREX CAP
      • NEWMULT CAP
      • OFLODAZOLE CAP
      • KINVOX-500 & KINVOX-750
      • KINTHOMOL TAB
      • KINRATN TABLETS BP 2mg
      • KINOTEM TAB & SUSPENSION
      • KINZOCAP 200MG TAB
      • KINOMAL 80/480 TAB
      • ZADOL TAB
      • ZADOL FORTE TAB
      • KINZOLIN TAB
      • KINZOLE CAPSULES 20 MG
      • KINCEF 1g INJECTION
      • KINCEF 1.5g INJECTION
    • Wholesale & Distribution

+234 803 4946 900


  • Home
  • Gallery
  • Products
    • KENACIN TAB
    • BEETHER INJECTION
    • CHYMOK TAB
    • KINBREX CAP
    • NEWMULT CAP
    • OFLODAZOLE CAP
    • KINVOX-500 & KINVOX-750
    • KINTHOMOL TAB
    • KINRATN TABLETS BP 2mg
    • KINOTEM TAB & SUSPENSION
    • KINZOCAP 200MG TAB
    • KINOMAL 80/480 TAB
    • ZADOL TAB
    • ZADOL FORTE TAB
    • KINZOLIN TAB
    • KINZOLE CAPSULES 20 MG
    • KINCEF 1g INJECTION
    • KINCEF 1.5g INJECTION
  • Wholesale & Distribution

KINTHOMOL TAB

Methocarbamol Tablets USP

Composition : Each uncoated Tablet Contains : 

Methocarbamol        USP 500 mg.

Excipients         q.s.


INDICATIONS:

Kinthomol  Tablets USP is indicated as an adjunctive therapy for the relief of  discomfort associated with acute painful musculoskeletal conditions.

Kinthomol Tablets USP is also indicated for control of muscle spasm in tetanus.


DOSAGE & ADMINISTRATION:

For Oral use:

Initial: 1.5 gm.(i.e. 3 Tablets) 4 times daily.

Maintenance: 1 gm. (2 Tablets) 4 times daily.

For  the first time 48 to 72 hours, 6 gm / day is recommended (For severe  conditions 8 gm. Daily may be administered). Thereafter reduce to  approximately 4 gm. daily.


USAGE IN TETANUS:

Kinthomol  does not replace the usual procedure of debridement tetanus antitoxin,  penicillin, tracheotomy, attention to fluid balance and supportive care.  Add Kinthomol injection to the regimen as soon as possible.


PHARMACOLOGY:

Kinthomol  is a centrally acting skeletal muscle relaxant. Its mechanism of action  has been established, but may be sue to general CNS depression. The  drug has no direct action on the contractile mechanism of striated  muscle, motor endplate or nerve fiber, it does not directly relax tense  skeletal muscles.

Kinthomol is rapidly absorbed from the gastro intestinal tract following oral administration. 

Kinthomol has an onset of action of 30 minutes. 

Peak  plasma levels occur approximately 2 hours after administration of 2 gm.  The half-life is from 1 to 2 hours.  Kinthomol is metabolized, probably  in the liver and excreted in urine primarily as the glucuronide and  sulphate conjugates of its metabolites.

A small amount is excreted in faeces.


ADVERSE REACTIONS :

Lightheadedness,  dizziness, drowsiness, nausea, urticaria, rash conjunctivitis with  nasal congestion, blurred vision, headache, fever.


PRECAUTIONS & WARNINGS:

a) Kinthomol may impair concentration; patients so affected should not drive or operate machinery.

b)  Kinthomol is not recommended during pregnancy, especially during early  pregnancy or in women who may become pregnant, unless potential benefits  outweigh potential hazards.

c) It is not known whether Kinthomol is excreted in breast milk. 

Exercise caution when administering to nursing women.

d) Safety and efficacy of Kinthomol in children below 12 years old has not been established, except in tetanus.

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OVERDOSAGE :

Overdosage often is conjunction with alcohol or other CNS depressants, is marked by coma and other signs of CNS depression.


 TREATMENT OF OVERDOSE :

Treatment  is essentially supportive. Simple isolated seizures may require only  observation and supportive care. Repetitive seizures or status  epilepticus require therapy. Diazepam i.v. is generally the agent of  choice, parentral barbiturates have also been used.


 CONTRAINDICATIONS 

Kinthomol  is contraindicated in hypersensitive patients, in coma or pre-coma  states, brain, damage, myasthenia gravis or in patients with a history  of epilepsy.
 

DRUG INTERACTIONS:

The  CNS effects of Kinthomol may be potentiated by concomitant  administration of other CNS depressants such as alcohol.Kinthomol has  also been stated to potentiate the effects of anorectics,  antimuscarinics and some psychotropic agents.Kinthomol may cause color  interference in certain screening tests for 5 hydroxy indole acetic acid  (5-HIAA) and vanillylmandelic acid (VMA)


.STORAGE CONDITIONS:

Keep in a cool, dry place, below 25ºC. Protect from light.


PRESENTATION :

Kinthomol Tablets USP: A strip of 10 tablets. in Mono Pack.


NAFDAC  Reg. No. : B4-5365

Manufactured by:

Brussels Laboratories Pvt. Ltd.33, Changodar Ind. Estate, Changodar-382 210.Dist. Ahmedabad (Gujarat, India)


Marketed by

KINGZY PHARMACEUTICALS LTD.

142 Okporo Road, Port Harcourt, 

Rivers State, NIGERIA

Mfg. Lic. No. : G/1369 

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Kingzy Pharmaceuticals Limited

 

Office:Corporate

 Marshall Investment House, 500 East West Road,

Near Omega House, Rumuodara 

Port Harcourt, Rivers State, Nigeria. 

Registered Office

+234-803 494 6900 +234-805 901 3884 kiingzypharma@gmail.com,

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